American tegumentary leishmaniasis: correlations among immunological, histopathological and clinical parameters
نویسندگان
چکیده
منابع مشابه
American tegumentary leishmaniasis: correlations among immunological, histopathological and clinical parameters*
BACKGROUND American tegumentary leishmaniasis has an annual incidence of 1 to 1.5 million cases. In some cases, the patient's immune response can eliminate the parasite, and the lesion spontaneously resolves. However, when this does not occur, patients develop the disseminated form of the disease. OBJECTIVE To investigate the association between clinical, laboratory and pathological findings ...
متن کاملAmerican tegumentary leishmaniasis: an uncommon clinical and histopathological presentation*
We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms. The histological sections showed epithelial atrophy and a large number of structures consistent with Leishmania sp. amastigotes within macrophages. Treat...
متن کاملAmerican tegumentary leishmaniasis: antigen-gene polymorphism, taxonomy and clinical pleomorphism.
Multi-locus enzyme electrophoresis is the current gold standard for the genetic characterisation of Leishmania. However, this method is time-consuming and, more importantly, cannot be directly applied to parasites present in host tissue. PCR-based methods represent an ideal alternative but, to date, a multi-locus analysis has not been applied to the same sample. This has now been achieved with ...
متن کاملOral Manifestations in the American Tegumentary Leishmaniasis
INTRODUCTION American tegumentary leishmaniasis (ATL) can affect the skin or mucosa (mucocutaneous leishmaniasis - MCL) including the oral cavity. MCL oral lesions are often confused with other oral diseases, delaying diagnosis and specific treatment, and increasing the likelihood of sequelae. Thus, increasing the knowledge of the evolution of ATL oral lesions can facilitate its early diagnosis...
متن کامل[Immunoglobulin isotype and IgG subclass profiles in American tegumentary leishmaniasis].
The present work investigated the serum antibody profiles in 37 patients with American tegumentary leishmaniasis, who were attended at Hospital de Clinicas - Universidade Federal de Uberlandia, MG, Brazil. The immunoglobulin class and IgG subclass profiles were analyzed by indirect ELISA using Leishmania (Leishmania) amazonensis soluble antigen. The antibody avidity was determined by 6 M urea t...
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ژورنال
عنوان ژورنال: Anais Brasileiros de Dermatologia
سال: 2014
ISSN: 0365-0596
DOI: 10.1590/abd1806-4841.20142226